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Body Detox: What It Means and How Your Body Clears Toxins

SOMA Longevity Sciences

SOMA Longevity Sciences

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Body Detox: What It Means and How Your Body Clears Toxins

In short: The liver and kidneys help process and eliminate many foreign chemicals; the route and speed depend on the substance. A 2015 review of commercial detox diets found very little clinical evidence for them. Foot-pad toxin-removal claims lack reliable supporting evidence. If you have a real exposure, the useful step is finding and stopping the source, with testing where a doctor advises it.

What does body detox mean?

Body detox has two meanings. In a hospital, detoxification means treating poisoning or withdrawal from a substance. In marketing, it usually means a diet, juice, tablet or machine said to flush out unnamed "toxins".

The first is a medical process with measured results. The second is rarely specific. A good first question for any detox product is: which toxin, and how was its removal measured?

What are xenobiotics?

Xenobiotics are substances foreign to the body's normal chemistry. These include medicines and environmental pollutants; 'foreign' does not automatically mean harmful. The word comes from the Greek xenos, meaning stranger.

Other examples include alcohol, pesticide residues, food additives and chemicals in tobacco smoke. Your body has dedicated systems for dealing with them.

How do the liver and kidneys clear xenobiotics?

The liver makes fat-soluble chemicals water-soluble, and the kidneys and bile then carry them out. A review in Clinics in Liver Disease describes three phases. These phases are not compulsory consecutive steps: some substances undergo only one metabolic phase, while others leave unchanged.

Phase 1: changing the molecule. Enzymes, mainly in the liver, add or expose a chemical group on the molecule. This prepares it for the next step. The product can sometimes be more reactive than the original, which is one reason phase 2 matters.

Phase 2: attaching a tag. Liver enzymes attach a small molecule to it, a step called conjugation. One of these tags is glutathione, the body's main built-in antioxidant. Conjugation usually makes the substance easier to excrete.

Phase 3: moving it out. Transporter proteins move the product out of cells. It then leaves through the gut in bile, through the kidneys in urine, or through the lungs.

The kidneys finish the job for water-soluble waste. They filter the blood continuously and pass waste out in urine.

Metals are different. They cannot be broken down, because they are elements. Lead can stay stored in bone for a long time, and cadmium can stay in the kidney long after exposure ends. No diet or drink changes that quickly, which is why confirmed metal poisoning is a medical matter. Our chelation guide explains this further.

Do detox diets remove toxins from the body?

There is very little clinical evidence that they do. A 2015 critical review in the Journal of Human Nutrition and Dietetics looked at commercial detox diets. It found only a handful of clinical studies, with flawed methods and small numbers of people, and said that, to the authors' knowledge, no randomised controlled trial had tested these diets in humans.

Eating well does matter for health. It simply does not follow that a short "cleanse" removes a named toxin. If a programme cannot say what it removes and how that was measured, it has not shown a detox effect.

Do juice cleanses work, and are they risk-free?

A juice cleanse is a period of living mainly on juices, and it has no established toxin-clearing effect. It also carries risks for some people.

One published case described a 65-year-old woman who developed serious kidney damage after a cleanse of oxalate-rich green juices. Oxalate is a natural plant substance that can form crystals in the kidney. She also had risk factors, including past gastric bypass surgery and recent long antibiotic treatment. One case does not show how often this happens, but it is a reason for people with kidney disease or past bowel surgery to speak to a doctor first.

Do detox foot pads and foot baths work?

There is no good evidence that they draw toxins out through the feet. In 2009, the United States Federal Trade Commission charged the marketers of one foot-pad brand with deceptive advertising. It alleged that claims about drawing toxins and heavy metals out of the body were false or had no evidence behind them when made.

Ionic foot baths have been measured directly. In a small study, six healthy participants had four sessions, and researchers tested the water, urine and other samples. They concluded that the machine did not appear to cause toxic elements to leave through the feet.

A pad or water that changes colour does not show that anything left your body.

Are liver detox tablets, teas and syrups useful?

There is no good reason for a person with a healthy liver to take a "liver detox" product, and some herbal products carry their own risk. Your liver does not need cleaning out. It is an active organ, not a filter that clogs.

Products sold for the liver are not automatically harmless. In the Indian Network of Drug-Induced Liver Injury, which followed 1,288 patients with liver injury caused by a medicine or product, complementary and alternative medicines were the second largest group of causes, at 13.9%.

Yellow eyes, dark urine or a swollen abdomen need a doctor, not a detox. Tell your doctor about every tablet, tea and syrup you take, including herbal ones.

When does exposure testing make sense?

Exposure testing makes sense when there is a specific reason to suspect a specific substance. It is most useful in cases such as these:

  • work with lead, batteries, smelting, or solvents and pesticides

  • long use of a metal-containing traditional preparation

  • drinking water from a source known to carry arsenic

  • a long, unexplained illness, together with a possible exposure

The aim is to find a source and stop it. SOMA lists toxin and heavy-metal screening. Tests must target a suspected substance; what a result reveals depends on the sample, exposure timing and substance involved.

Everyday steps that lower exposure are often the most direct: stopping tobacco, cutting down alcohol, reviewing supplements with your doctor, and checking your water source if you rely on a borewell.

How does SOMA describe its own therapies?

SOMA describes each therapy by what it does in the body, and offers it only after testing and screening. A doctor decides from your results, not from a menu.

EBOO with hemofiltration. EBOO stands for extracorporeal blood oxygenation and ozonation. Blood flows from one arm through a sterile, single-use circuit, where a filtration membrane removes unwanted components from the plasma, the liquid part of blood. The blood is enriched with oxygen and treated with a controlled dose of medical-grade ozone, then returns through the other arm. A session typically runs 45 to 60 minutes under continuous clinical supervision.

At SOMA it is a physician-prescribed therapy inside a wider protocol, never a stand-alone purchase, and it is not offered as a treatment or cure for any disease. Screening is mandatory. Some cardiovascular, clotting and blood-pressure profiles, and pregnancy, exclude it. Individual responses vary, and yours is measured.

Glutathione IV. Glutathione is one component your doctor can choose in IV nutrient therapy. A drip raises blood levels within minutes. The body then breaks it down and uses the building blocks in its own supply. Our glutathione guide explains who needs extra assessment first.

How does a SOMA doctor decide what is right for you?

At SOMA, a doctor starts with a long conversation about your history, symptoms and earlier reports. Tiredness or feeling "toxic" can have many roots, so testing comes before any treatment discussion.

Your doctor suggests only the tests that make sense for you, and explains the results in plain language. Depending on what they show, the plan may combine food, sleep, movement and targeted supplements with medical therapies, as one part of a plan built around you. If you do not need treatment, your doctor will tell you.

SOMA centres in Mumbai and New Delhi

SOMA doctors see patients at two centres:

  • Mumbai: A-507, Kohinoor Square, N.C. Kelkar Marg, Shivaji Park, Dadar West, Mumbai 400028. Phone +91 98671 94033.

  • New Delhi: E-354, Greater Kailash II, New Delhi 110048, serving Delhi NCR and Gurugram. Phone +91 87969 92001. More about the New Delhi centre.

The New Delhi centre is independently operated under licence from SOMA Longevity Sciences, and its own doctors lead care there. Both centres follow the same SOMA assessment and diagnostic standards. Online consultations are also available. Contact either centre.

Questions people ask

What is the meaning of body detox?

In medicine, detox means treating poisoning or withdrawal. In marketing, it usually means a product said to flush out toxins. Your liver and kidneys already clear most foreign chemicals, every day.

What are xenobiotics?

Xenobiotics are chemicals foreign to the body, such as medicines, alcohol, pesticides and pollutants. The liver converts many of them into water-soluble forms, which then leave in bile or urine.

Do detox diets remove toxins from the body?

A critical review found very little clinical evidence that commercial detox diets do, and no randomised controlled trials in humans at the time of the review. The studies it found were small and had flawed methods.

Do I need a liver detox?

A healthy liver does not need a detox product, and complementary and alternative medicines are a recorded cause of liver injury in India. If you are worried about your liver, a doctor can check it with blood tests and review what you take.

Is there a body detox centre in Mumbai or Delhi?

Ask any centre which toxin it measures and how. Doctors at SOMA's centres in Dadar West, Mumbai and Greater Kailash II, New Delhi start with your history and testing, before any treatment is discussed.

Related guides

Sources

  1. Almazroo OA, Miah MK, Venkataramanan R. Drug metabolism in the liver. Clinics in Liver Disease 2017;21(1):1–20. https://pubmed.ncbi.nlm.nih.gov/27842765/

  2. Klein AV, Kiat H. Detox diets for toxin elimination and weight management: a critical review of the evidence. Journal of Human Nutrition and Dietetics 2015;28(6):675–686. https://pubmed.ncbi.nlm.nih.gov/25522674/

  3. Kennedy DA, Cooley K, Einarson TR, Seely D. Objective assessment of an ionic footbath (IonCleanse): testing its ability to remove potentially toxic elements from the body. Journal of Environmental and Public Health 2012;2012:258968. https://pubmed.ncbi.nlm.nih.gov/22174728/

  4. Makkapati S, D'Agati VD, Balsam L. "Green smoothie cleanse" causing acute oxalate nephropathy. American Journal of Kidney Diseases 2018;71(2):281–286. https://pubmed.ncbi.nlm.nih.gov/29203127/

  5. Devarbhavi H, Joseph T, Sunil Kumar N, et al. The Indian Network of Drug-Induced Liver Injury: etiology, clinical features, outcome and prognostic markers in 1288 patients. Journal of Clinical and Experimental Hepatology 2021;11(3):288–298. https://pubmed.ncbi.nlm.nih.gov/33994711/

  6. Federal Trade Commission. FTC charges marketers of Kinoki Foot Pads with deceptive advertising; seeks funds for consumer redress. 28 January 2009. https://www.ftc.gov/news-events/news/press-releases/2009/01/ftc-charges-marketers-kinoki-foot-pads-deceptive-advertising-seeks-funds-consumer-redress

  7. Chakif D, Furrer J. Heavy metal toxicity in clinical and environmental health: sources, mechanisms, diagnostics, and evidence-based management of mercury, lead, cadmium, and arsenic. International Journal of Molecular Sciences 2026;27(8):3513. https://pubmed.ncbi.nlm.nih.gov/42074156/

  8. Aebi S, Assereto R, Lauterburg BH. High-dose intravenous glutathione in man: pharmacokinetics and effects on cyst(e)ine in plasma and urine. European Journal of Clinical Investigation 1991;21(1):103–110. https://pubmed.ncbi.nlm.nih.gov/1907548/

This article is for education and general information. It is not a substitute for a medical consultation, diagnosis or treatment. Results vary by individual biology.

Wondering what your own results would show? Start with a conversation.